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It is primarily used in treating post menopausal symptoms. - Submited to the Article Codex Free Content Directory. Estriol can be taken out of the formulations and they&'ll still work well because they also contain estradiol, another natural estrogen, but, ironically they probably won&'t be as safe. Estriol has some protective properties that balance I take premarin .9 mg and wonder if and/or when there ever may be a generic for this. I tried estradiol and OMG! I was SO nauseated and the hot flashes were horrendous! After 2 days on the med, I switched back to premarin and did fine. Estradiol. (See Estrogen.) Estrogen. Estradiol. Female hormones from pregnant mares’ urine. Considered a drug. Can have harmful systemic effects if used by children. Used for reproductive problems and in birth control pills and Premarin Could you please discuss concert diego san soma pros and cons of prednisone vs prednisolone? 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